Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978 Jun 8;273(5662):443-6.
doi: 10.1038/273443a0.

The alpha-helix dipole and the properties of proteins

W G Hol, P T van Duijnen, H J Berendsen

The alpha-helix dipole and the properties of proteins

W G Hol et al. Nature. .

Abstract

Phosphate moieties bind frequently at N-termini of helices in proteins. It is shown that this corresponds with an optimal interaction of the helix dipole and the charged phosphate. This favourable arrangement may have been discovered several times during evolution. In some enzymes, the helix dipole might be used in catalysis.

PubMed Disclaimer

LinkOut - more resources