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. 1978 Mar;85(3):268-75.
doi: 10.1016/s0161-6420(78)35668-2.

Dipivalyl epinephrine: a new pro-drug in the treatment of glaucoma

A I Mandell, F Stentz, A E Kitabchi

Dipivalyl epinephrine: a new pro-drug in the treatment of glaucoma

A I Mandell et al. Ophthalmology. 1978 Mar.

Abstract

The dansyl chloride technique in conjunction with thin layer chromatography and autoradiography has shown that dipivalyl epinephrine is a pro-drug in the human eye. Dipivalyl epinephrine appears to be a more effective epinephrine compound, in that it penetrates the cornea approximately 17 times greater than epinephrine.

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