Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1983;9(3):325-8.
doi: 10.1093/schbul/9.3.325.

Variability and the dopamine hypothesis of schizophrenia

J G Csernansky, C A Holman, L E Hollister

Variability and the dopamine hypothesis of schizophrenia

J G Csernansky et al. Schizophr Bull. 1983.

Abstract

The dopamine hypothesis of schizophrenia is usually presented in a static, rather than dynamic fashion. We propose that increased dopaminergic activity may represent a stage of a dynamic schizophrenic process rather than its cause. Dopamine, as well as other neurotransmitters, responds in an adaptive fashion to stimuli that perturb the homeostasis of the brain. One such stimulus could be an epileptic focus in the temporal lobe. Other such stimuli undoubtedly also exist.

PubMed Disclaimer

Publication types

MeSH terms