Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1983 Jul-Aug;29(4):16-22.

[Effect of phosphatidyl serine on conversion of fibrinogen to fibrin]

[Article in Russian]
A Sh Byshevskiĭ, P I Leven, S R Sokolovskiĭ
  • PMID: 6623990

[Effect of phosphatidyl serine on conversion of fibrinogen to fibrin]

[Article in Russian]
A Sh Byshevskiĭ et al. Vopr Med Khim. 1983 Jul-Aug.

Abstract

Phosphatidyl serine inhibited the conversion of fibrinogen into fibrin, catalyzed by thrombin, following the pattern of coupling inhibition. The inhibition was caused by the property of phosphatidyl serine of forming an exhibiting low activity complex with thrombin as well as by interaction of the lipoid with monomeric fibrin; as a result of this process phosphatidyl serine inhibited both enzymatic and non-enzymatic pathways of the fibrin formation. Administration of phosphatidyl serine into animal circulation led to a decrease in fibrinogen consumption, provoked by simultaneous injection of thrombin. Phosphatidyl serine appears to serve as a circulating anticoagulant.

PubMed Disclaimer

Publication types