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. 1978 May;5(5):1571-80.
doi: 10.1093/nar/5.5.1571.

Light scattering measurements supporting helical structures for chromatin in solution

A M Campbell, R I Cotter, J F Pardon
Free PMC article

Light scattering measurements supporting helical structures for chromatin in solution

A M Campbell et al. Nucleic Acids Res. 1978 May.
Free PMC article

Abstract

Laser light scattering measurements have been made on a series of polynucleosomes containing from 50 to 150 nucleosomes. Radii of gyration have been determined as a function of polynucleosome length for different ionic strength solutions. The results suggest that at low ionic strength the chromatin adopts a loosely helical structure rather than a random coil. The helix becomes more regular on increasing the ionic strength, the dimension resembling those proposed by Finch and Klug for their solenoid model.

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