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. 1983 Sep;140(4):316-22.
doi: 10.1007/BF00442672.

Gaucher disease--Norrbottnian type. Neurodevelopmental, neurological, and neurophysiological aspects

S Blom, A Erikson

Gaucher disease--Norrbottnian type. Neurodevelopmental, neurological, and neurophysiological aspects

S Blom et al. Eur J Pediatr. 1983 Sep.

Abstract

Neurodevelopmental, neurological and neurophysiological aspects of the Norrbottnian type of Gaucher disease (type III) were studied in 22 patients. The findings were related to clinical stages and to whether or not the patients had been splenectomized. Neurological abnormalities were mainly found in splenectomized patients who had passed the first decade of life. The EEG findings were not diagnostic for the disease, but changes were more common in the advanced stages and among splenectomized patients. The patterns of development of neurological and neurophysiological features indicate that CNS deposition of glucosylceramide increases after splenectomy, and favor a restrictive attitude towards surgery.

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References

    1. J Bone Joint Surg Am. 1951 Jul;33-A(3):698-707 - PubMed
    1. Eur J Pediatr. 1980 Mar;133(2):107-18 - PubMed
    1. Acta Paediatr. 1962 Mar;51:137-54 - PubMed
    1. Neurology. 1980 Feb;30(2):152-9 - PubMed
    1. J Neurol Neurosurg Psychiatry. 1960 Aug;23:207-13 - PubMed

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