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. 1983 Nov;156(2):524-8.
doi: 10.1128/jb.156.2.524-528.1983.

Transport and processing of staphylococcal alpha-toxin

Transport and processing of staphylococcal alpha-toxin

R K Tweten et al. J Bacteriol. 1983 Nov.

Abstract

Two larger precursors to staphylococcal alpha-toxin were identified and partially characterized. Both precursor proteins were present on the cell membrane at very low levels and appeared to be rapidly processed to the mature form. Dinitrophenol inhibited processing such that the two precursors accumulated in the membranes, whereas little extracellular (mature) alpha-toxin is formed. The peptide maps of the 35S-labeled peptides from extracellular alpha-toxin and the two precursors were almost identical. The larger precursor protein contained four additional peptides and the smaller precursor protein contained three additional peptides not found in the extracellular toxin.

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References

    1. Biochemistry. 1973 Jul 3;12(14):2672-7 - PubMed
    1. Infect Immun. 1976 Mar;13(3):982-6 - PubMed
    1. Mol Cell Biochem. 1979 Feb 9;23(3):143-52 - PubMed
    1. Infect Immun. 1981 Dec;34(3):900-7 - PubMed
    1. J Bacteriol. 1983 Jan;153(1):297-303 - PubMed

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