Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1983 Sep;72(9):1071-2.
doi: 10.1002/jps.2600720926.

In vivo-in vitro correlations for trisulfapyrimidine suspensions

L K Mathur, J L Colaizzi, J M Jaffe, R I Poust, V P Shah

In vivo-in vitro correlations for trisulfapyrimidine suspensions

L K Mathur et al. J Pharm Sci. 1983 Sep.

Abstract

A UV method is described for measuring total sulfa drug concentration in dissolution samples. This in vitro measurement was found to correlate well with several in vivo parameters obtained after administration of commercial trisulfapyrimidine suspensions to humans. The UV method, which is rapid, simple, inexpensive and easily automated, is recommended for studying the dissolution of trisulfapyrimidine suspensions.

PubMed Disclaimer

Publication types

LinkOut - more resources