Primer recognition by avian myeloblastosis virus RNA-directed DNA polymerase
- PMID: 66328
- PMCID: PMC515668
- DOI: 10.1128/JVI.21.3.1236-1239.1977
Primer recognition by avian myeloblastosis virus RNA-directed DNA polymerase
Abstract
Tryptophanyl-tRNA was specifically labeled at the 3' end with [3H]tryptophan and cleaved in half with RNase under denaturing conditions, and the 3' half was shown to hybridize exclusively at the 5' end of avian myeloblastosis virus RNA. The RNA-dependent DNA polymerase of avian myeloblastosis virus is capable of efficiently binding the 3' half of the primer molecule.
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