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Comparative Study
. 1983 Aug;19(2):365-7.
doi: 10.1016/0091-3057(83)90066-7.

Cardiovascular and plasma prolactin responses to stereoisomers of phencyclidine

M A Bayorh, D Lozovsky, K C Rice, T R Burke Jr, I J Kopin
Comparative Study

Cardiovascular and plasma prolactin responses to stereoisomers of phencyclidine

M A Bayorh et al. Pharmacol Biochem Behav. 1983 Aug.

Abstract

The effect of phencyclidine (PCP) and dextro- and levorotatory isomers of its derivatives 1-(1-phenylcyclo-hexyl)-3-methylpiperidine [(+)-PCMP and (-)-PCMP] (5 mg/kg, SC) on blood pressure (BP), heart rate (HR) and plasma prolactin (PRL) were examined. PCP and (+)-PCMP but not (-)-PCMP increased BP and HR and suppressed plasma PRL.

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