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. 1983 Oct 15;130(1):247-51.
doi: 10.1016/0042-6822(83)90135-6.

Lymphocytic choriomeningitis virus. VI. Isolation of a glycoprotein mediating neutralization

M Bruns, J Cihak, G Müller, F Lehmann-Grube

Lymphocytic choriomeningitis virus. VI. Isolation of a glycoprotein mediating neutralization

M Bruns et al. Virology. .

Abstract

A structural glycoprotein of lymphocytic choriomeningitis virus was obtained in pure form by immunoaffinity chromatography using a monoclonal antibody with high neutralizing activity. It blocked neutralization of viral infectivity by antibody and in polyacrylamide gel electrophoresis it migrated with an apparent molecular weight of 44 X 10(3). We conclude that the isolated material is identical with the previously described gp44 (GP-1).

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