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Comparative Study
. 1978 Mar;15(2):223-36.
doi: 10.1177/030098587801500209.

Transmissible murine colonic hyperplasia

S W Barthold, G L Coleman, R O Jacoby, E M Livestone, A M Jonas
Comparative Study

Transmissible murine colonic hyperplasia

S W Barthold et al. Vet Pathol. 1978 Mar.

Abstract

After exposure to a variant of Citrobacter freundii, suckling and adult mice developed transmissible murine colonic hyperplasia of the same degree of severity. Mucosal hyperplasia was most severe 2 to 3 weeks after inoculation and then regressed. Suckling mice had a high mortality because of secondary inflammatory and erosive changes. Severe hyperplasia was characterized by mitotic activity along the entire crypt column and surface mucosa.

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