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. 1983 Oct;72(10):1178-81.
doi: 10.1002/jps.2600721018.

Bayesian approach to bioequivalence assessment: an example

H Fluehler, A P Grieve, D Mandallaz, J Mau, H A Moser

Bayesian approach to bioequivalence assessment: an example

H Fluehler et al. J Pharm Sci. 1983 Oct.

Abstract

The statistical methods required for a Bayesian analysis of bioequivalence are outlined and numerically illustrated. The analysis consists of the calculation of the posterior probability, given the experimental results, that the ratio of true means of a new and a standard formulation of a drug with respect to some biological response lies in a given interval. Nomograms helpful for the calculation of these probabilities are provided.

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