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. 1983:86:99-102.
doi: 10.1007/978-3-642-82025-0_18.

First experimental and clinical results of isolated liver perfusion with cytotoxics in metastases from colorectal primary

K Aigner, H Walther, J Tonn, A Wenzl, R Hechtel, G Merker, K Schwemmle

First experimental and clinical results of isolated liver perfusion with cytotoxics in metastases from colorectal primary

K Aigner et al. Recent Results Cancer Res. 1983.

Abstract

In two patients suffering from numerous liver metastases in both lobes from colorectal primary isolated liverperfusion with 5-fluorouracil was performed. By means of a special cannulation system the hepatic artery and the portal vein were arterialized. The patients recovered rapidly after the operation. Sonographic measurements, CAT scans, pulse cytophotometry, and second-look operations with histological examinations of metastatic tissue verified extensive tumor regression. No complications occurred within 6 months after the perfusion treatment.

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