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. 1983 Nov;18(5):461-4.
doi: 10.1111/j.1365-3083.1983.tb00878.x.

Stress causes reduced natural killer activity in mice

H J Aarstad, G Gaudernack, R Seljelid

Stress causes reduced natural killer activity in mice

H J Aarstad et al. Scand J Immunol. 1983 Nov.

Abstract

The natural killer (NK) activity of spleen cells from C57B1/10 mice subjected to standardized stress conditions was reduced when compared with that of untreated controls. Both the total number of nucleated spleen cells and their cytotoxic activity against an NK-sensitive target were reduced. The reduction appeared after induction of stress, and the NK activity was reduced throughout an 8-day stress period.

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