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. 1977 Apr 2;1(8014):730-1.
doi: 10.1016/s0140-6736(77)92171-7.

Effect of a single dose of dimethyl sulphoxide on renal amyloidosis

M Ravid, I K Keizman, E Sohar

Effect of a single dose of dimethyl sulphoxide on renal amyloidosis

M Ravid et al. Lancet. .

Abstract

An amyloid-like fibrillar substance was obtained under certain chemical conditions from the urine of 11 patients with amyloid nephropathy who had been given a test dose of dimethyl sulphoxide. This fibrillar material could not be produced in the urine from 9 patients with proteinuria due to other causes. This finding may be useful in the diagnosis of amyloid nephropathy and could lead to a new approach to thearpy.

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