Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1983 Dec;37(4):305-9.
doi: 10.1136/jech.37.4.305.

Mortality from thyrotoxicosis in England and Wales and its association with the previous prevalence of endemic goitre

D I Phillips, D J Barker, P D Winter, C Osmond

Mortality from thyrotoxicosis in England and Wales and its association with the previous prevalence of endemic goitre

D I Phillips et al. J Epidemiol Community Health. 1983 Dec.

Abstract

The distribution of mortality from thyrotoxicosis among women in England and Wales during 1968-78 correlates with the previous prevalence of endemic goitre. Mortality from the disease rose to a peak in the decade 1931-40 and then declined. This peak affected all age groups and can be attributed to the high fatality from surgery before the introduction of preoperative iodine to prevent thyroid crisis. An apparent cohort effect, whereby cohorts born from 1871 to 1886 experienced the highest mortality, may be explained by generations with a high prevalence of endemic goitre becoming exposed to increasing dietary iodine intake in later life.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Stat Med. 1982 Jul-Sep;1(3):245-59 - PubMed
    1. Ned Tijdschr Geneeskd. 1954 Jan 9;98(2):81-9 - PubMed
    1. Lancet. 1973 Oct 20;2(7834):894-5 - PubMed
    1. Br J Nutr. 1982 May;47(3):381-90 - PubMed
    1. J Chronic Dis. 1961 Jan;13:22-38 - PubMed