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. 1983 Nov;25(2-3):223-9.
doi: 10.1016/0378-1119(83)90226-3.

Presence of mitochondrial-DNA-like sequences in the human nuclear DNA

T Tsuzuki, H Nomiyama, C Setoyama, S Maeda, K Shimada

Presence of mitochondrial-DNA-like sequences in the human nuclear DNA

T Tsuzuki et al. Gene. 1983 Nov.

Abstract

Two lambda phage clones carrying contiguous human nuclear DNA sequences with extensive homology to non-contiguous human mitochondrial 16S ribosomal RNA sequences were isolated from a human gene library. The one clone carried mitochondrial-DNA(mtDNA)-like sequences flanked with two kinds of repetitive nuclear DNA sequences and the other carried mtDNA-like sequences, between unique nuclear DNA sequences and repetitive DNA sequences of Alu-family. These results demonstrate that mtDNA-like sequences are present in human nuclear DNA.

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