[Anaphylactic type of accidents due to myorelaxing agents during general anesthesia. Clinical and biological study]

Abstract

Six patients who had suffered a reaction to the administration of muscle relaxants at the time of induction of general anaesthesia were explored using skin tests, the Prausnitz-Küstner reaction, the blastic transformation test, the Shelley test and the basophil histamine release test. Fifteen normal subjects were used as controls. The patients who had suffered a reaction showed considerable cutaneous hypersensitivity to muscle relaxants. None of the biological tests carried out revealed an immunological mechanism.