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Comparative Study
. 1983 Dec;54(4):275-87.
doi: 10.1007/BF01234480.

A new approach to practical acute toxicity testing

D Lorke
Comparative Study

A new approach to practical acute toxicity testing

D Lorke. Arch Toxicol. 1983 Dec.

Abstract

A method for the investigation of the acute toxicity of an unknown chemical substance, with an estimation on the LD50, is described. Using this, it is possible to obtain with 13 experimental animals adequate information on the acute toxicity and on the LD50. This method has no limitations and applies to drugs, agricultural and industrial chemicals. It can be used for every route of administration.

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References

    1. J Assoc Off Anal Chem. 1979 Jul;62(4):864-73 - PubMed
    1. J Toxicol Environ Health. 1977 Dec;3(5-6):797-809 - PubMed
    1. Arch Toxicol. 1981 Apr;47(2):77-99 - PubMed

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