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Comparative Study
. 1983 Dec;1(4):331-3.
doi: 10.1016/0732-8893(83)90009-3.

Detection of Clostridium difficile cytotoxin in HEp-2 and CHO cell lines

P R Murray, C J Weber
Comparative Study

Detection of Clostridium difficile cytotoxin in HEp-2 and CHO cell lines

P R Murray et al. Diagn Microbiol Infect Dis. 1983 Dec.

Abstract

The detection of Clostridium difficile cytotoxin was compared in two established cell lines; Chinese hamster ovary (CHO) and a human epithelial line, HEp-2. All specimens with positive toxin assays were detected with the CHO cell line, whereas only one-half of positive specimens were detected with the HEp-2 cells.

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