The appearance of an IgD-like molecule on pig lymphocytes during ontogeny
- PMID: 6667918
- DOI: 10.1007/BF02879687
The appearance of an IgD-like molecule on pig lymphocytes during ontogeny
Abstract
An IgD-like molecule was found on the surface of pig fetal lymphocytes using guinea pig anti-human IgD antisera and indirect immunofluorescence. The binding of antiIgD antisera could be specifically inhibited with human IgD. Surface IgD-like molecules were found later in ontogeny than surface IgM (after about 70 d of gestation in the spleen). There is evidence for their endogenous origin. The number of lymphocytes bearing IgD-like molecules rapidly increased during ontogeny.
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