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. 1978 Jun 23;529(3):380-6.
doi: 10.1016/0005-2760(78)90082-6.

The fatty acids of human sebaceous gland phosphatidylcholine

M E Stewart, D T Downing, P E Pochi, J S Strauss

The fatty acids of human sebaceous gland phosphatidylcholine

M E Stewart et al. Biochim Biophys Acta. .

Abstract

The fatty acids of human sebaceous gland phosphatidylcholine were examined by gas chromatography and by analysis of the double bond positions in the C-16 and C-18 monoenes. Compared to phosphatidylcholine from other organs, sebaceous gland phosphatidylcholine was found to be deficient in essential fatty acids and poly-unsaturated fatty acids. The relatively large mono-unsaturated fatty acid fraction consisted predominantly of fatty acids with delta6- and delta8-unsaturation. Analysis indicates that the fatty acids of sebaceous gland phospholipids are predominantly of types synthesized in sebaceous glands.

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