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. 1978 Apr;29(2):51-3.

Prostaglandins released into human burn blister fluid

S Sugiyama, I Norimatsu, M Kobayashi, T Ozawa, H Aoyama, K Suzuki, Y Izawa
  • PMID: 667287

Prostaglandins released into human burn blister fluid

S Sugiyama et al. Biomedicine. 1978 Apr.

Abstract

Acidic lipids were isolated from human burn blister fluid and the presence of prostaglandins E and F compounds was demonstrated by the thin-layer chromatography. Prostaglandins E1, E2 and F2alpha were identified and quantitatively determined by radioimmunoassay and by gas-liquid chromatography/mass spectrometry. Analyses on burn blister fluid obtained from 35 patients with skin burn indicated an extensive release of prostaglandins into the blister after burn injury in a few hours. The high levels of prostaglandins in burn blister fluid decreased gradually during 24 hours after burn.

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