[Comparative studies of the analytical reliability of the results of various hematologic tests]

Abstract

In connection with the implementation of new methods and apparatuses for the determination of hemoglobin, hematocrit, erythrocytes, MCV, MCH, MCHC and leukocytes, the reproducibility was studied in series, compared with the arithmetical means and standard deviations and correlation analysis of the results was performed. Manual and automated, to various degrees, investigation methods were used. The reproducibility in hemoglobin determination was very good, with no significant differences between the means of the different methodical variants. The microhematocrit method provided a very good reproducibility for hematocrit, with significant differences in the means of the three methods used. The reproducibility of erythrocytes was between 1,09% and 2,34%. VK of leukocytes ranged from 2,0% to 5,73%. The differences between the means of the different methods for erythrocyte count and, in the majority of the cases, for leukocytes, allow the statistically significant comparability of the results. The best reproducibility from the mathematical indices of erythrocytes was obtained for MCHC. The correlation analysis showed a positive correlation between the methods compared in all parameters studied.