[Problem of amyotrophy]

Abstract

Clinical and electroneuromyographic studies of 1771 patients with diseases of the nervous and neuromuscular systems revealed disruption of the trophic supply to the skeletal muscles in cases of damage to both the segmento-peripheral neuromotor apparatus and vegetative and somatic segmental and suprasegmental formations. Electroneuromyographic indicators of the amyotrophic process include a decrease in the amplitude of the maximal M-response and a reduced number of functional motor units. In hyperkinetic syndromes, a paradoxical elevation of these indices is observed, which seems to be associated with "an alleviating trophotropic effect" exerted by striatal system impairment.