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Case Reports
. 1978 May;32(2):233-42.

Treatment of Goodpasture's disease by plasma exchange and immunosuppression

C P Swainson, J S Robson, S J Urbaniak, A J Keller, A B Kay
Case Reports

Treatment of Goodpasture's disease by plasma exchange and immunosuppression

C P Swainson et al. Clin Exp Immunol. 1978 May.

Abstract

Three cases of Goodpasture's disease are described who were treated with intensive plasma exchange and immunosuppression. There was no improvement in renal function and the patients required chronic haemodialysis, but renal function did recover with treatment for recurrence of disease in a transplanted kidney. Anti-GBM antibody levels were not controlled and substantial reduction in fibrinogen and complement were only achieved with daily treatment. A controlled trial of this regime is urgently required.

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