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. 1983 Mar 1;209(3):893-6.
doi: 10.1042/bj2090893.

Further evidence for a flexible and highly expanded spheroidal model for mucus glycoproteins in solution

S E Harding, A J Rowe, J M Creeth

Further evidence for a flexible and highly expanded spheroidal model for mucus glycoproteins in solution

S E Harding et al. Biochem J. .

Abstract

The flexible and greatly expanded roughly spherical model for mucus glycoproteins proposed earlier, on the basis of hydrodynamic and n.m.r. data, is supported by new hydrodynamic results on a bronchial glycoprotein from a cystic-fibrosis patient. Furthermore, images from electron microscopy of this molecule and a lower-molecular-weight mucus glycoprotein (which closely resembles a glycopolypeptide) appear to be at least consistent with this model.

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