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. 1983;45(5):257-61.
doi: 10.1159/000275652.

cis-Diamminedichloroplatinum: a cytostatic with an ototoxic effect

S Hartwig, U Pettersson, J Stahle

cis-Diamminedichloroplatinum: a cytostatic with an ototoxic effect

S Hartwig et al. ORL J Otorhinolaryngol Relat Spec. 1983.

Abstract

Among 74 patients treated with cis-diamminedichloroplatinum in total doses of 130-590 mg/m2 body surface area, high tone hearing loss was observed in 3. The caloric and rotatory responses were reduced in 3 other patients. Optokinetic responses remained normal in all patients.

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