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. 1983 Jun;6(3):277-9.
doi: 10.1097/00000421-198306000-00004.

m-AMSA in epithelial carcinoma of the ovary. A Southwest Oncology Group study

R D Hilgers, S S Legha, F J Panettiere, D S Alberts

m-AMSA in epithelial carcinoma of the ovary. A Southwest Oncology Group study

R D Hilgers et al. Am J Clin Oncol. 1983 Jun.

Abstract

Twenty-three patients with advanced heavily pretreated epithelial carcinoma of the ovary were treated with m-AMSA. Eleven patients received a mean of 2.3 courses at a dose of 40 mg/m2 X 3 days q 21 days and 12 patients received a mean of 4.3 courses at a dose of 30 mg/m2 X 3 days q 21 days intravenously. One (5%) partial response in 22 fully evaluable patients was observed. Toxicity was mild and well tolerated. We conclude that m-AMSA is a relatively inactive drug in the treatment of epithelial ovarian carcinoma.

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