Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1983 Oct;28(10):893-6.
doi: 10.1007/BF01317039.

Peptide histidine isoleucine (PHI). A secretagogue in porcine intestine

A A Anagnostides, K Manolas, N D Christofides, Y Yiangou, R B Welbourn, S R Bloom, V S Chadwick

Peptide histidine isoleucine (PHI). A secretagogue in porcine intestine

A A Anagnostides et al. Dig Dis Sci. 1983 Oct.

Abstract

PHI (peptide histidine isoleucine) is a recently identified porcine peptide, present in large quantities in the intestine, which has sequence homologies with VIP, an established intestinal secretagogue, and with secretin, glucagon, and GIP. The effects of PHI on jejunal, ileal, and colonic fluid and electrolyte transport were studied in the pig. PHI appears to be an intestinal secretagogue inducing a reversible net secretion of fluid and electrolytes in jejunum and ileum and less marked effects in the colon.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. FEBS Lett. 1980 Jun 2;114(2):240-2 - PubMed
    1. Gastroenterology. 1978 Dec;75(6):1051-4 - PubMed
    1. Dig Dis Sci. 1983 Jun;28(6):507-12 - PubMed
    1. Life Sci. 1980 Nov 24;27(21):1947-51 - PubMed
    1. Proc Natl Acad Sci U S A. 1981 Nov;78(11):6603-7 - PubMed