doi: 10.1016/0012-1606(83)90214-2.
Gene coding for a lens-specific protein, delta-crystallin, is transcribed in nonlens tissues of chicken embryos
- PMID: 6688594
- DOI: 10.1016/0012-1606(83)90214-2
Item in Clipboard
Gene coding for a lens-specific protein, delta-crystallin, is transcribed in nonlens tissues of chicken embryos
Dev Biol.
1983 Nov.
Abstract
The question of whether or not delta-crystallin gene (delta-gene) is transcribed in tissues of chicken embryos other than lens was examined by Northern blot analysis, using cloned delta-crystallin cDNA as a probe. delta-Crystallin mRNA was detected in neural retinas, brains, and limb buds of 3.5-day-old embryos. However, the distribution of delta-gene transcripts is limited to lens only in posthatched chickens. It was indicated that the ratio of large delta-crystallin RNA, probably precursor RNA, to mature delta-crystallin mRNA is always much higher in nonlens tissues.
Similar articles
-
Independent regulation of two coexpressed delta-crystallin genes in chick lens and nonlens tissues.Exp Cell Res. 1991 Apr;193(2):370-4. doi: 10.1016/0014-4827(91)90109-8. Exp Cell Res. 1991. PMID: 2004651
-
Differential expression of the two delta-crystallin genes in lens and non-lens tissues: shift favoring delta 2 expression from embryonic to adult chickens.Dev Dyn. 1993 Feb;196(2):114-23. doi: 10.1002/aja.1001960205. Dev Dyn. 1993. PMID: 8364221
-
delta- and beta-Crystallin mRNA levels in the embryonic and posthatched chicken lens: temporal and spatial changes during development.Dev Biol. 1985 May;109(1):72-81. doi: 10.1016/0012-1606(85)90347-1. Dev Biol. 1985. PMID: 3987967
-
Developmental regulation of the chicken delta 1-crystallin gene: analysis by transgenesis and gene dissection.Cell Differ Dev. 1988 Nov;25 Suppl:53-7. doi: 10.1016/0922-3371(88)90100-1. Cell Differ Dev. 1988. PMID: 3061593 Review.
-
Crystallin genes: specialization by changes in gene regulation may precede gene duplication.J Struct Funct Genomics. 2003;3(1-4):131-7. J Struct Funct Genomics. 2003. PMID: 12836692 Review.
Cited by
-
Gene sharing by delta-crystallin and argininosuccinate lyase.Proc Natl Acad Sci U S A. 1988 May;85(10):3479-83. doi: 10.1073/pnas.85.10.3479. Proc Natl Acad Sci U S A. 1988. PMID: 3368457 Free PMC article.
-
Tissue-specific regulation of a chicken delta-crystallin gene in mouse cells: involvement of the 5' end region.EMBO J. 1985 Sep;4(9):2201-7. doi: 10.1002/j.1460-2075.1985.tb03915.x. EMBO J. 1985. PMID: 3000763 Free PMC article.
-
Stimulation of crystallin synthesis in embryonic brain cells in culture.Rouxs Arch Dev Biol. 1986 Jan;195(1):15-21. doi: 10.1007/BF00444037. Rouxs Arch Dev Biol. 1986. PMID: 28305273
-
The pattern of protein and glycoprotein synthesis in presumptive lens and non-lens ectoderm of the chicken embryo.Rouxs Arch Dev Biol. 1991 Jun;200(1):38-44. doi: 10.1007/BF02457639. Rouxs Arch Dev Biol. 1991. PMID: 28305916
-
Lens-specific expression and developmental regulation of the bacterial chloramphenicol acetyltransferase gene driven by the murine alpha A-crystallin promoter in transgenic mice.Proc Natl Acad Sci U S A. 1985 Dec;82(23):7815-9. doi: 10.1073/pnas.82.23.7815. Proc Natl Acad Sci U S A. 1985. PMID: 3865198 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
