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Comparative Study
. 1983;168(3):307-13.
doi: 10.1007/BF00304269.

The right auricle of the heart is an endocrine organ. Cardiodilatin as a peptide hormone candidate

W G Forssmann, D Hock, F Lottspeich, A Henschen, V Kreye, M Christmann, M Reinecke, J Metz, M Carlquist, V Mutt
Comparative Study

The right auricle of the heart is an endocrine organ. Cardiodilatin as a peptide hormone candidate

W G Forssmann et al. Anat Embryol (Berl). 1983.

Abstract

A new polypeptide hormone candidate regulating vascular smooth muscle function was extracted from porcine atrial tissue. The purification steps were followed by a bioassay. The hormonally active substance has been analyzed and found to be a small polypeptide exhibiting a molecular weight of about 7500 and is named "cardiodilatin" (CDD). Further chemical data on this new hormone will be published elsewhere. A partial amino acid sequence of cardiodilatin is offered and shows that among the well known hormones or neuropeptides, none exhibit a homologue partial sequence.

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