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. 1984 Jan;49(1):283-6.
doi: 10.1128/JVI.49.1.283-286.1984.

Effect of novobiocin on mycoplasma virus L2 replication

S K Poddar, J Maniloff

Effect of novobiocin on mycoplasma virus L2 replication

S K Poddar et al. J Virol. 1984 Jan.

Abstract

L2 is a temperate mycoplasma virus containing 11.8 kilobase pairs of negatively superhelical double-stranded DNA. We observed L2 DNA with less superhelicity in novobiocin-treated cells than that in untreated cells. However, although no change in viral DNA superhelicity could be found in novobiocin-treated novobiocin-resistant cells, L2 production decreased in these novobiocin-treated cells.

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