Effect of novobiocin on mycoplasma virus L2 replication
- PMID: 6690717
- PMCID: PMC255456
- DOI: 10.1128/JVI.49.1.283-286.1984
Effect of novobiocin on mycoplasma virus L2 replication
Abstract
L2 is a temperate mycoplasma virus containing 11.8 kilobase pairs of negatively superhelical double-stranded DNA. We observed L2 DNA with less superhelicity in novobiocin-treated cells than that in untreated cells. However, although no change in viral DNA superhelicity could be found in novobiocin-treated novobiocin-resistant cells, L2 production decreased in these novobiocin-treated cells.
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