Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1984 Jan;17(1):86-8.
doi: 10.1111/j.1365-2125.1984.tb05004.x.

Plasma lipid fractions during long-term monotherapy with the ISA-containing beta-adrenoceptor blocker bopindolol in hypertensive patients

P Van Brummelen, P Bolli, M I Koolen, H B Staehelin, F R Bühler
Clinical Trial

Plasma lipid fractions during long-term monotherapy with the ISA-containing beta-adrenoceptor blocker bopindolol in hypertensive patients

P Van Brummelen et al. Br J Clin Pharmacol. 1984 Jan.

Abstract

The influence of bopindolol monotherapy on blood pressure and plasma lipid fractions was investigated in 24 hypertensive patients. Bopindolol lowered blood pressure and heart rate significantly. When compared with placebo no changes were found in the plasma concentrations of total cholesterol, LDL cholesterol and HDL cholesterol. Plasma triglycerides were significantly increased after 4 and 8 weeks but not after 12 weeks of bopindolol. It is concluded that bopindolol is an effective and well tolerated beta-adrenoceptor blocker in hypertensive patients. The fact that it does not lower HDL cholesterol could be a potential advantage.

PubMed Disclaimer

References

    1. J Lipid Res. 1970 Nov;11(6):583-95 - PubMed
    1. Lancet. 1980 Jul 5;2(8184):4-6 - PubMed
    1. Lancet. 1981 Apr 4;1(8223):744-7 - PubMed
    1. J Cardiovasc Pharmacol. 1983 May-Jun;5(3):426-9 - PubMed
    1. Eur J Clin Pharmacol. 1982;22(6):491-3 - PubMed

Publication types