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. 1978 Mar;14(3):290-3.
doi: 10.1007/BF02616038.

Transforming activities of trichloroethylene and proposed industrial alternatives

P J Price, C M Hassett, J I Mansfield

Transforming activities of trichloroethylene and proposed industrial alternatives

P J Price et al. In Vitro. 1978 Mar.

Abstract

Three chlorinated hydrocarbons, proposed or already in use as industrial substitutes for the hydrocarbon trichloroethylene, were tested for in vitro transforming potential in a Fischer rat embryo cell system (F1706), which previously has been shown to be sensitive to transformation by chemical carcinogens. Trichloroethylene and the three substitutes (1, 1, 1 trichloroethane, tetrachloroethylene and methylene chloride) all were found to induce transformation, the three substitutes being equal or more efficient transforming agents.

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References

    1. In Vitro. 1975 Mar-Apr;11(2):107-16 - PubMed
    1. Cancer Lett. 1976 May;1(5):259-62 - PubMed

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