doi: 10.1016/0378-4274(84)90156-5.
Cytotoxicity of cyclophosphamide and acrylamide in glioma and neuroblastoma cell lines cocultured with liver cells
- PMID: 6701912
- DOI: 10.1016/0378-4274(84)90156-5
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Cytotoxicity of cyclophosphamide and acrylamide in glioma and neuroblastoma cell lines cocultured with liver cells
Toxicol Lett.
1984 Mar.
Abstract
A method for the cocultivation of nervous system cells with liver cells has been developed. When acrylamide was tested using the cocultivation procedure no significant liver metabolism-mediated changes in the cytotoxicity in C6 culture were detected. In neuroblastoma N1E115 cultures the toxicity was increased by induced chick hepatocytes at high acrylamide concentrations.
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