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. 1984 Mar;20(3):251-6.
doi: 10.1016/0378-4274(84)90156-5.

Cytotoxicity of cyclophosphamide and acrylamide in glioma and neuroblastoma cell lines cocultured with liver cells

A C Ericsson, E Walum

Cytotoxicity of cyclophosphamide and acrylamide in glioma and neuroblastoma cell lines cocultured with liver cells

A C Ericsson et al. Toxicol Lett. 1984 Mar.

Abstract

A method for the cocultivation of nervous system cells with liver cells has been developed. When acrylamide was tested using the cocultivation procedure no significant liver metabolism-mediated changes in the cytotoxicity in C6 culture were detected. In neuroblastoma N1E115 cultures the toxicity was increased by induced chick hepatocytes at high acrylamide concentrations.

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