New antibiotic U-64846: fermentation, isolation and characterization
- PMID: 6706857
- DOI: 10.7164/antibiotics.37.96
New antibiotic U-64846: fermentation, isolation and characterization
Abstract
Antibiotic U-64846 is a new entity with the molecular formula C18H35C1N4O9 (MW 486). It is a very water soluble, reddish solid which decomposes above 300 degrees C and which is air-sensitive. The antibiotic is produced by Streptomyces braegensis and it inhibits a variety of Gram-positive bacteria. Acidic hydrolysis gave 3,7-diaminoheptanoic acid. The antibiotic gives 1H NMR, 13C NMR, IR and UV spectra which indicate it is not closely related to known antibiotic families.
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