doi: 10.1099/0022-1317-65-4-761.
Purification and characterization of GP90, one of the envelope glycoproteins of respiratory syncytial virus
- PMID: 6707612
- DOI: 10.1099/0022-1317-65-4-761
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Purification and characterization of GP90, one of the envelope glycoproteins of respiratory syncytial virus
J Gen Virol.
1984 Apr.
Abstract
The large glycoprotein, GP90, of respiratory syncytial virus (RSV) was purified by affinity chromatography using a monoclonal antibody. Hyperimmune rabbit antiserum directed specifically to the purified GP90 neutralized RSV to high titre but did not inhibit fusion of previously infected cells. 125I-labelled GP90 bound rapidly to HEp-2 cells in an unsaturable manner; binding was inhibited by the hyperimmune rabbit antiserum.
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