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. 1984 May;68(5):316-20.
doi: 10.1136/bjo.68.5.316.

Normal tear protein profiles and age-related changes

J I McGill, G M Liakos, N Goulding, D V Seal

Normal tear protein profiles and age-related changes

J I McGill et al. Br J Ophthalmol. 1984 May.

Abstract

The specific and non-specific tear proteins have been analysed by means of the ELISA technique to establish the normal and age-related values. There is a linear and related decline of lysozyme and lactoferrin with age, and a similar but unrelated reduction in tear volume. IgA levels gradually decline, while caeruloplasmin and IgG both increase after the fifth decade. The results suggest that tear IgG and caeruloplasmin are probably transudates from the serum, that IgA is secreted independently of tear volume, and that lysozyme and lactoferrin are secreted at the same site but independently of tear volume.

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References

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