doi: 10.1016/0009-2797(84)90140-6.
Hepatic cholesterol in lead nitrate induced liver hyperplasia
- PMID: 6713595
- DOI: 10.1016/0009-2797(84)90140-6
Item in Clipboard
Hepatic cholesterol in lead nitrate induced liver hyperplasia
Chem Biol Interact.
1984 Mar.
Abstract
Wistar rats treated with lead nitrate were used in these experiments to provide evidence of the possible correlation between hyperplasia, induced cholesterol synthesis and the levels of glucose-6-phosphate dehydrogenase (G-6-PD) in the liver. Lead treatment increases liver weight, hepatic cholesterol esters and the relative content of free cholesterol. An increase of the incorporation of tritiated water in free and cholesterol esters was also observed. The effect of lead resulted in an increase of hepatic G-6-PD at all times considered. The correlation between these parameters and hyperplasia are discussed.
Similar articles
-
Cell cholesterol esters and high-density lipoprotein plasma levels during liver hyperplasia in choline-fed male and female rats.Int J Exp Pathol. 2000 Aug;81(4):241-8. doi: 10.1046/j.1365-2613.2000.00159.x. Int J Exp Pathol. 2000. PMID: 10971745 Free PMC article.
-
Modifying influence of fasting on liver hyperplasia induced by lead nitrate.Res Commun Chem Pathol Pharmacol. 1990 Apr;68(1):103-16. Res Commun Chem Pathol Pharmacol. 1990. PMID: 2345800
-
Changes in serum and hepatic cholesterol in lead-induced liver hyperplasia.Toxicol Pathol. 1984;12(2):162-7. doi: 10.1177/019262338401200208. Toxicol Pathol. 1984. PMID: 11488298
-
Multiple molecular forms of rat liver glucose-6-phosphate dehydrogenase during liver hyperplasia induced by lead nitrate.Res Commun Chem Pathol Pharmacol. 1990 Feb;67(2):279-88. Res Commun Chem Pathol Pharmacol. 1990. PMID: 2333415
-
Liver hyperplasia and regression after lead nitrate administration.Toxicol Pathol. 1984;12(1):89-95. doi: 10.1177/019262338401200115. Toxicol Pathol. 1984. PMID: 6494739
Cited by
-
Relationship between DNA and cholesterol synthesis in kidney after refeeding.Experientia. 1988 Sep 15;44(9):760. doi: 10.1007/BF01959154. Experientia. 1988. PMID: 3416992
-
Cell cholesterol esters and high-density lipoprotein plasma levels during liver hyperplasia in choline-fed male and female rats.Int J Exp Pathol. 2000 Aug;81(4):241-8. doi: 10.1046/j.1365-2613.2000.00159.x. Int J Exp Pathol. 2000. PMID: 10971745 Free PMC article.
-
Serum lipoproteins during bone marrow hyperplasia after phenylhydrazine administration in rats.Int J Exp Pathol. 1990 Oct;71(5):671-5. Int J Exp Pathol. 1990. PMID: 2206988 Free PMC article.
-
Role of cholesterol synthesis and esterification in the growth of CEM and MOLT4 lymphoblastic cells.Biochem J. 1997 Feb 1;321 ( Pt 3)(Pt 3):603-8. doi: 10.1042/bj3210603. Biochem J. 1997. PMID: 9032443 Free PMC article.
-
Does G6PD deficiency protect against cancer? A critical review.J Epidemiol Community Health. 1987 Jun;41(2):89-93. doi: 10.1136/jech.41.2.89. J Epidemiol Community Health. 1987. PMID: 3309118 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous
