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Case Reports
. 1984;66(2-3):230-3.
doi: 10.1007/BF00286607.

Regional mapping of clotting factors VII and X to 13q34. Expression of factor VII through chromosome 8

J de Grouchy, M D Dautzenberg, C Turleau, S Beguin, F Chavin-Colin
Case Reports

Regional mapping of clotting factors VII and X to 13q34. Expression of factor VII through chromosome 8

J de Grouchy et al. Hum Genet. 1984.

Abstract

Blood clotting factors were investigated in a patient with trisomy 8 mosaicism, a patient with an r(13), and a patient with distal trisomy 13q. Results are compatible with the assignment of the structural genes of factors VII and X to 13q34 and the existence of a regulatory mechanism associated with chromosome 8 controlling the expression of factor VII alone.

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