Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1984 Mar;73(3):366-9.
doi: 10.1002/jps.2600730319.

Deaza analogues of adenosine as inhibitors of blood platelet aggregation

I Antonini, G Cristalli, P Franchetti, M Grifantini, S Martelli, F Petrelli

Deaza analogues of adenosine as inhibitors of blood platelet aggregation

I Antonini et al. J Pharm Sci. 1984 Mar.

Abstract

A number of deaza analogues of adenosine were prepared and tested as inhibitors of platelet aggregation induced by ADP and collagen to investigate the structure-activity relationships in this class of nucleoside analogues. The results showed that the presence of a 6-amino group and nitrogen atoms at positions 3 and 7 of the purine moiety are required for inhibitory activity.

PubMed Disclaimer

LinkOut - more resources