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. 1984 Apr;308(5961):705-9.
doi: 10.1038/308705a0.

Single base deletion in the vasopressin gene is the cause of diabetes insipidus in Brattleboro rats

H Schmale, D Richter

Single base deletion in the vasopressin gene is the cause of diabetes insipidus in Brattleboro rats

H Schmale et al. Nature. 1984 Apr.

Abstract

In rats with hereditary hypothalamic diabetes insipidus (Brattleboro rats) the gene for the vasopressin precursor lacks a single G residue in the protein-coding region. The mutation gives rise to an open reading frame predicting a hormone precursor having a different C-terminus.

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