Prophylaxis of Candida albicans infection in neutropenic mice with liposome-encapsulated amphotericin B
- PMID: 6721469
- PMCID: PMC185519
- DOI: 10.1128/AAC.25.3.366
Prophylaxis of Candida albicans infection in neutropenic mice with liposome-encapsulated amphotericin B
Abstract
The efficacy of liposome-encapsulated amphotericin B in the prophylaxis of disseminated Candida albicans infections in neutropenic mice was studied. The administration of liposome-encapsulated amphotericin B was associated with protection against infection with C. albicans when used at doses of greater than or equal to 2 mg of amphotericin B per kg of body weight. Neither empty liposomes nor free amphotericin B showed prophylactic efficacy.
References
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical