[Changes in the microcirculatory bed of the mesentery in the rat in the intestinal form of acute radiation disease (experimental morphologic study)]

Abstract

Total mesentery preparations of the rat after single total irradiation at the dose levels of 15 and 30 Gy were examined by V. V. Kupriyanov 's method and staining by N.E. Yarigin and S.V. Panchenko . Monotonous pathomorphological changes characteristic of microcirculation disorders were revealed such as blood overdistribution into the venous part of microvasculature prestasis , stasis and lymphostasis. Apart from these qualitative alterations, morphometry of certain parts of microvasculature was performed and some indexes and ratios were calculated. Changes of quantitative parameters were as follows: increase of the capillaries, postcapillaries and venules diameter, increase of their surface and volume, increase of diameter of pericapillary diffusion zone; decrease of the correlation ratio between total arteriolar influx and total venular blood passage within a mesentery segment; decrease of the calculated linear speed of blood in capillaries, postcapillaries and venulas .