Alphaxolone-alphadolone anaesthesia in laboratory animals
- PMID: 672181
- DOI: 10.1258/002367778780953206
Alphaxolone-alphadolone anaesthesia in laboratory animals
Abstract
The anaesthetic steroid combination alphaxolone-alphadolone is a well-established short-acting injectable agent for cats and primates. It can be recommended for intravenous administration to rats, rabbits, neonatal pigs, mice and hamsters. It has limited value in mice and hamsters by the intraperitoneal route, but provides sedation in ferrets and neonatal pigs when injected intramuscularly. It can be given repeatedly or continuously to maintain anaesthesia for long periods without the development of tolerance or cumulation.