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. 1984 Apr;45(4):659-62.
doi: 10.1016/S0006-3495(84)84207-1.

Mechanical hypothesis of sperm penetration

D P Green, R D Purves

Mechanical hypothesis of sperm penetration

D P Green et al. Biophys J. 1984 Apr.

Abstract

Sperm have generally been supposed to penetrate the zona pellucida surrounding the mammalian egg with the aid of a protease, acrosin. Difficulties associated with this view are discussed and an alternative, mechanical hypothesis introduced. The calculated force exerted by individual sperm is too small to permit the rupture of any but the weakest of secondary chemical bonds. Mechanical progress through the zona must rely on stress relaxation in a viscoelastic medium. The known properties of the zona appear to be consistent with such a mechanism of penetration.

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References

    1. Am J Anat. 1968 Sep;123(2):329-58 - PubMed
    1. J Reprod Fertil. 1967 Jun;13(3):577-8 - PubMed
    1. J Reprod Fertil. 1970 Oct;23(1):193-6 - PubMed
    1. Anat Rec. 1972 Sep;174(1):9-19 - PubMed
    1. Biol Reprod. 1972 Oct;7(2):288-96 - PubMed

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