Sex differences in sensitization to cocaine-induced rotation
- PMID: 6723788
- DOI: 10.1016/0014-2999(84)90442-4
Sex differences in sensitization to cocaine-induced rotation
Abstract
Sensitization to cocaine- and d-amphetamine-induced rotation was studied in male and female rats. A single injection of cocaine (20 mg/kg) sensitized female rats to a subsequent dose administered 1 or 7 days later; sensitivity returned to normal within 14 days. Sensitization to cocaine did not occur in male rats nor to d-amphetamine in either sex.
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